Notable News Archives

January 2024 Notable News

This month doctors and scientists are applying knowledge learned from cancer patients and research to improve cancer treatment. Doctors must juggle many things when a patient with a chronic illness is diagnosed with cancer. Scientists are learning how forever chemicals encourage the spread of cancer. A new peptide has been designed to inhibit a protein that can stop the growth of 75% of cancerous tumors.

How Do Chronic Diseases Affect Cancer Treatment?

A cancer diagnosis is challenging enough. But having a chronic disease, such as diabetes, high blood pressure, heart disease, or kidney problems, can affect how doctors treat your cancer reports Everyday Health. Cancer diagnosis can happen to older adults who already have many coexisting conditions that require medications. Drug interactions can occur with cancer medicines and chronic condition medications, causing side effects. Some chronic health problems like diabetes increase the risk of infection, making it harder to recover from some cancer surgeries. Some surgeries to remove cancers can make chronic health problems worse, like lung cancer removal affecting chronic lung disease patients. Chronic health problems can eliminate some cancer patients from qualifying for clinical trials. Physicians have a scoring system tool to use that helps choose appropriate treatments for cancer patients. It is the ECOG, Eastern Cooperative Oncology Group scoring system. Doctors can reduce chemotherapy medications doses to avoid complications that can arise from combining chemotherapy with medications for chronic illness. Some cancer patients must prioritize other health issues and treat the cancer when it is safe to do so. It is a careful balance that involves good communication between the patient and the doctor. Click here for the full story.

“Forever Chemicals” Encourage Cancer to Spread Around the Body

In a new study by researchers at the Yale school of public health, two “forever chemicals” spurred cancer cells in the lab to migrate to new positions, an indication that the chemicals could contribute to cancer metastasis in living organisms reports earth.com. These industrial chemicals don’t break down and have toxic effects on the body. The chemicals (PFAS) are found in drinking water, indoor dust, cleaning products, and even interior coatings. Levels of PFAS are showing up in the blood of newborn babies, in sea life, and in bird eggs. Firefighters are having an increased rate of cancer from exposure to PFAS through their jobs. Scientists study the effects of PFAS chemicals using experiments with metabolomics, a tool that studies small molecules. These chemicals are found to cause effects at a cellular level that show metastatic potential. Click here for the full story.

Scientists Succeed in Stopping Cancer Engine Fueling 75% of Tumors

Scientists have developed a peptide that holds promise in controlling the activity of the MYC protein, a key contributor to exacerbating 75% of human cancer cases reports Interesting Engineering. This peptide inhibits the function of a protein MYC; in cancer the MYC’s activity is not regulated properly. MYC helps promote cancer growth when not regulated. When it is regulated, MYC transcribes RNA and DNA. It has a globular shape, making it difficult for drugs to bind to it. This new research has found a peptide that can bind to MYC. Scientists are using nanoparticles to deliver the peptide into cells, connecting to the MYC protein once inside the cells. This knowledge opens possibilities to design new cancer treatments by limiting the proteins activity in cancer cells. Click here for the full story. 

December 2023 Notable News

This month brings scientists closer to advancing cancer treatments with many new discoveries. A new epitope in tumors has been found and it can be a target for treatments to kill cancer. Cellfree DNA in the blood has been discovered as a new way to monitor cancer in patients. An old drug, lidocaine, has been found to be effective to assist other therapies in fighting cancer. 

‘Time Bomb’ Cancer Treatment Could Blow the ‘Doors’ off Tumor Cells in a Major Scientific Breakthrough

The new method triggers a time bomb in tumors that could open them up to new treatment, US researchers found. It targets cells that line a receptor on the cells’ blood vessel called Fas – or- CD95 that causes the death of that cell when triggered by the right antibody reports The US Sun. Immunotherapy is a valuable cancer treatment, but it helps a small number of patients because the T cells cannot break through most solid tumors. Scientists have now found an epitope, called Fas or CD95 that is part of the tumor cell, and the T cell can recognize it. Scientists can develop antibodies to activate CD95 to assist with CAR T-cell therapy. This new approach can make this immunotherapy effective for more patients, including those with solid tumors. Click here for the full story. 

How We Could Test for Cancer, Even Without a Tumor Sample

There are many different combinations or patterns of mutation that cause cancer, but the most important lesson is cancer occurs because of mutations in the DNA of a cell reports Newsbreak. Two very important kinds of genes are tumor suppressing genes and oncogenes, if they mutate it can allow cancer to grow. Cells put DNA into the bloodstream when they die and from cancer cells growing. Scientists have made machines sensitive enough to detect this amount of DNA in the blood. This technology is still in clinical trials to determine the limit of cell free DNA and the progression of the cancer to get detected. This technology will be helpful to monitor the effectiveness of cancer patients’ treatment over time, and it will be helpful for patients with a high risk of developing cancer. Click here for the full story. 

Lidocaine Makes Cancer Cells Self-Destruct, Study Finds

Doctors may be able to improve outcomes for patients with head and throat cancers simply by injecting the common local anesthetic lidocaine near the site of their tumors, according to a new University of Pennsylvania study reports Freethink . Lidocaine has been found to activate T2R14, a bitter taste receptor. T2R14 is found in many cancer cells causing cancer death for head and neck cancers. This activates two mechanisms, mitochondrial calcium ion overload and proteasome inhibition, causing the cancer cells to die. This new information is valuable to the development of new cancer treatments. The lidocaine would not be used alone, it would be given in combination with other cancer therapies. Click here for the full story. 

August 2023 Notable News

This month the key to cancer treatment for patients and doctors is knowledge. People diagnosed with cancer have protection in place for their job under The Americans with Disabilities Act. Scientists out of Denmark have discovered a new type of T cells that help fight cancer. During studies on a protein, GRP78, scientists discovered a new mechanism of how cancer spreads.

Protections for People with Cancer: Top 5 Things to Know About Your Rights as a Cancer Patient Under The Americans with Disabilities Act

The Americans with Disabilities Act offers protection for people battling cancer or who have a history of cancer. The federal law prohibits discrimination against qualified people with disabilities, including people diagnosed with cancer or who had cancer that is a remission. Reports SurvivorNet. Employers must make reasonable accommodations for patients undergoing cancer treatments. This accommodation includes allowing employees with cancer the ability to leave for medical appointments. It also allows them to take extra breaks as needed to take medications or if there is fatigue due to treatment. Employers can deny accommodation requests if it causes a significant expense or poor performance from the employee. Employers are not allowed to ask new job applicants if they have had cancer or have it currently. FMLA (Federal Family and Medical Leave Act) allows cancer patients to take unpaid leave and still protect their job position and their health insurance. This act also protects family members who are caring for cancer patients. Click here to read more.

Newly Discovered Superior T-cells Might Kill Tumors in Late-Stage Cancer Patients

A study out of Denmark has found new information about T-cells, which helps the body find and kill cells responsible for causing cancerous tumors. Our findings really surprised us, as nobody knew that individual T-cells could recognize cancer cells via several different cancer associated proteins simultaneously. These multi-pronged cells could respond to most types of cancer as cancers only need to express one of the aberrant targets to be identified as dangerous and killed said Andy Sewell, a professor at Cardiff University’s Division of Infection and Immunity reports Interesting Engineering. This knowledge was discovered during work on (TIL) Tumor Infiltrating Lymphocyte therapy, which uses T-cells grown in a lab to treat tumors and late-stage cancers. These multi-pronged T-cells are in the blood of patients that have survived cancer. In TIL therapy, doctors take T-cells from the tumor and then grow them in a lab to put them back in the patient’s body. Scientists hope to use this knowledge to make more immunotherapies to treat cancer. Click here to read more.

Surprising Finding: Scientists Discover New, Unexpected Mechanism of Cancer Cell Spread

During research on the protein GPR78, the protein that regulates replication of viruses and cancer growth, scientists made a new discovery. Lee and her colleagues have now made an unexpected discovery that may eventually enable scientists to protect cells from that hostile takeover. Typically, GRP78 resides in part of the cell called the endoplasmic reticulum. But when cells are under stress, the chaperone protein migrates to the cell’s nucleus, where it alters gene activities and changes the behavior of the cell, allowing the cancer cells to become more mobile and invasive reports SciTechDaily. Scientists used a high-resolution microscope and biochemical analysis to observe and confirm the new information about GRP78. They found GRP78 is involved in cell migration and invasion, which leads to a potential new cancer treatment that regulates GPR78. It was analyzed in lung, pancreatic, breast and colon cancers. These new findings also change the field of cell biology. It has enhanced knowledge about where the protein travels and what its new functions are. Click here to read more.

July 2023 Notable News

July brings hope to cancer patients with new knowledge, leading to helpful advances in oncology. Financial complications from cancer treatments are found to influence patient mortality. A new drug focusing on interrupting prostate cancer cell metabolism gives another option to prostate cancer patients. A scientific discovery of how bowel cancer evades immune response is helping scientists find a new treatment for the cancer.

Health-Related Social Needs Linked to Higher Risk of Death for Cancer Survivors

A new study by researchers at the American Cancer Society, (ACS) found health related social needs (HRSN) such as food insecurity and financial worry about paying for housing related expenses and other living necessities were associated with higher mortality risk among cancer survivors ages 18 to 64 reports Cancer Health. Cancer patients have large medical bills and often must pay a great deal of the expense out of pocket. There is a higher incidence of food insecurity in younger cancer survivors. One third of cancer survivors worry about how to pay housing and living expenses. The findings from this study suggest that an assessment needs to be done on cancer patients to identify their financial needs to help improve mortality rates. Click here for more information.

New Drug Shows Promise Against Treatment-Resistant Prostate Cancer

For this study, the researchers used a compound called Platin-L to break down a process that malignant prostate cancer cells use to fuel their growth and also to deliver the cisplatin directly into treatment-resistant cancer cells reports UPI News. Research done at the University of Miami tested it on human cancer cells and a mouse model of prostate cancer with promising results. Prostate cancer grows by getting energy from fat. Which is called fatty acid oxidation (FAO). Platin-L targets a protein that is involved in the FAO process. It interferes with cancers energy source to kill the cancer cells. The drug was administered orally inside of a nanoparticle that targets the prostate. Delivering the drug this way limits side effects to other parts of the body. It decreased side effects to the kidneys and liver, as well as lowered the risk for peripheral neuropathy. Click here for more information.

Bowel Cancer Treatment Hope as Scientists Solve Immune System Mystery

Researchers at the University of Glasgow and Cancer Research UK’s Beats Institute have discovered how bowel cancer. Blinds the immune system so it cannot see the cancer and renders it unable to destroy it reports The Independent. In the bell, when cells become cancerous, they no longer produce cells that allow for communicating the need for an immune response. These cells are called Gamma Delta T cells. Cancer cells are then bypassed and proliferate. This new knowledge will allow scientists to make a drug that makes the immune cells in the bowel see the cancer. Bowel cancer begins in the lining of the bowel. Scientists hope to use this information to trick the immune system to attack the cancer cells. Click here for more information.

March 2023 Notable News

March highlights the daily discoveries that are having a big impact on cancer treatment. Scientists have discovered ecDNA, a genetic material outside of chromosomes, that may lead to a new way to treat cancer. A geriatrician has developed an assessment tool to help doctors to choose more individualized cancer treatments. A new urine cancer test makes it easier for everyone to have access to cancer screening, even outside of the doctor’s office. Each day presents new opportunities for fighting the war on cancer.

Breakthrough ecDNA Discovery Could Revolutionize Cancer Research

A multi-disciplinary team of researchers has pinpointed the major role played by extrachromosomal DNA in the evolution of carcinogenic diseases. This kind of “external” oncogenes make cancer drug-resistance, and it could become one of the main targets for new and effective treatments in the future reports Tech Spot. This ecDNA is a piece of genetic material found outside of chromosomes in human cells. Genetic material outside of cells can be a sign of cancer. Researchers have found ecDNA’s role is to cause the cancer to spread rapidly, create tumors that are drug resistant, and can cause a relapse of the cancer. Oncogenes can hide in ecDNA for a period of time before becoming active again. Scientists are now using this knowledge to look at fighting cancer in a different way. Click to read the full story.

A Different Approach to Treating Cancer

Age is by far the biggest risk factor for getting cancer and it is the main factor in determining treatment options. Older patients are not all the same when it comes to activity and general health. There are patients in their 80’s that are healthier than some patients in their 60’s. Geriatrician Wiliam Dale’s team created a multi-dimensional assessment tool that looks at each patient’s physical and functional health reports WINK NEWS. The parameters of this tool look at patient nutrition, sleep, and mental health; focusing on the individual needs of the patient. The results of this new assessment have made for better outcomes for cancer patients. They experienced less chemotherapy toxicity, less nausea, and had better blood counts. The findings also showed that patients with hearing loss were at more risk for complications due to not hearing physician instructions clearly. Click to read the full story.

New Cancer Screening Urine Test has 99 Percent Accuracy Rate

Researchers from the Surface & Nano Materials Division of the Korea Institute of Materials Science recently developed a strip-type urine sensor capable of amplifying the light signal of metabolites in urine to diagnose cancer reports MITech News. The urine test needs no other analysis, making it simple to use outside of the hospital or doctor’s office. Cancer cells release metabolites, using a light scattering technique on the test strip, cancer can be detected using a small amount of urine. This test can detect cancer in various stages with 99% accuracy. It is a less invasive screening test, and the results can be used to get the patient to the doctor for further testing. Early screening for cancer allows for earlier treatment, making better patient outcomes. Click to read the full story.

October 2022 Notable News

The month of October brings exciting legislature to help patients afford available cancer treatments. Once passed, this legislature could make cancer treatment equitable and affordable while having a profound impact on the future. Scientists have created a new cancer vaccine for high risk melanoma patients that when given in combination with a cancer medication has encouraging results. Scientists have also found an experimental treatment for cancer that uses a modified herpes virus that has very promising early results. Lawmakers have an impact on cancer treatment by regulating laws that govern the insurance companies and are equally as important as the scientists finding the new cancer treatments.

Insurance Companies Shouldn’t Decide Which Cancer Treatment You Get. That Could Change.

There is a term that is familiar to cancer patients and providers, financial toxicity. Financial toxicity is when patients cannot afford the available treatment for their cancer. New options for cancer treatment are available; it used to be just IV medications but now there are oral medications to treat cancer. Insurance companies do not look at the two cancer treatments the same. They often deny coverage or impose huge out of pocket costs for the oral medication despite that doing so puts the patient at risk and violates the doctor-patient relationship by ignoring a prescribed treatment plan, in favor of saving money reports CharlotteObserver.com. There is legislation in front of congress called Cancer Drug Parity Act that could change this for cancer patients. This Act asks for the health plan to cover the level of cost share for all different kinds of cancer medications; it would assure the patients under the plan would get the treatment that they needed. There have been 40 states that have passed legislation regulating insurance plans, this act addresses the federal government. This legislation keeps the decision about cancer treatment between the patient and the oncologist. Click to read the full story.

A Cancer Vaccine for High-Risk Melanoma Patients

Scientists have created a cancer vaccine for Stage-2 melanoma that is custom for each patient. This vaccine is based on messenger RNA technology. The goal of Moderna’s vaccination is to stimulate the immune system to release killer T cells that specifically target particular mutations in patients reports HealthDigest.com. Scientists will give the vaccine with a drug already FDA approved called Keytruda. Keytruda is a monoclonal antibody that is already used to treat certain cancer types. Melanoma is a skin cancer that starts in the cells that make melanin and it is the deadliest form of skin cancer. Melanoma can spread to other parts of the body. It is caused by UV exposure from the sun or tanning bed and the UV rays damage DNA. Early detection increases survivability. Wearing sunscreen that blocks the damaging UV rays is important for prevention of melanoma. This vaccine in combination with Keytruda offers hope for people at high risk of developing melanoma. Click to read the full story.

Experimental Treatment With Modified Herpes Virus Cured Terminal Cancer

Scientists have managed to wipe out terminal cancer using a modified version of the herpes virus. A patient in a trial for the cancer-extermination virus saw his cancer completely disappear after the treatment. Over 15 months later, he has remained cancer free, according to the Institute of Cancer Research in London reports BGR.com. This treatment is still in it is early stages but is offering positive results and hope for cancer patients.There have been other viruses used to treat disease and cancer, the safety of the virus dosage is scientists biggest concern. The virus multiplies in the tumor and causes the tumor to burst from the inside out. The virus also increases the immune system’s ability to kill the cancer. Viruses help scientists target the cancer cells specifically. It is an example of looking at something that typically harms the body, in a new light to kill cancer. Click to read full story.

January 2022 Notable News

January offers hope. This year is starting with many new and exciting advances in the areas of cancer diagnosis, prevention, and treatment. A simple blood test has been found to detect if a patient has cancer and if it has metastasized in the body. There are now new clues as to how ovarian cancer begins and therefore might be prevented. Cancers have been found to be sorted by immune archetypes to make more precise immunotherapies to treat the cancer. It is encouraging to see the results of the prevention efforts, there is new research to show that the HPV cancer vaccine is saving lives.

Blood Test for Cancer Detection

A University of Oxford study outlines a new type of blood test that can be used to detect a range of cancers and whether these cancers have spread (metastasized) in the body, reports MedicalXpress.com. This blood test can be helpful in finding and staging cancer in the future for patients with non-specific symptoms that concern the provider. This is the first simple blood test to find metastatic cancer without any prior knowledge of the cancer type. A different technique is used with this blood test, it uses magnetic fields and radio waves to profile metabolites from the cancer tumors in the blood. Early diagnosis of cancer offers a better prognosis for patients, this blood test is easily, quickly, and affordably done by a primary doctor. Find more information here.

Clues into Ovarian Cancer

In a new study, scientists used stem cells created from the blood samples of women with BRCA mutations and ovarian cancer to fashion a model of fallopian tube tissue. There, they found first hints of ovarian cancer in the fallopian tube tissue, reports U.S.News.com. The hope is that by studying this tissue, they can predict ovarian cancer many years in advance of it developing. Ovarian cancer is one of the leading causes of cancer deaths for women due in part to the subtlety of the symptoms. Women with BRCA-1 mutations have a much higher risk of developing ovarian cancer. If scientists can find the abnormalities in the fallopian tube tissue, they may be able to stop the cancer. Using this fallopian tissue, they may be able to test which drug is most effective on the cancer without having to expose the patient to the drug first. The findings of this study may allow doctors to have early detection of ovarian cancer and have more effective treatments for the patient. Find more information here.

Sorting Cancers to Develop Precision Treatments

Using data from over 300 patient tumors, researchers have described 12 classes of ‘immune archetypes’ to classify cancer tumors, reports Sciencedaily.com. This study showed that cancers from different parts of the body respond similarly immunologically. Tumors are made up of immune cells that are supposed to fight the cancer cells, but with cancer cells, they overpower the body’s immune cells and take over. These ‘immune archetypes’ allow for doctors to personalize each patient’s cancer immunotherapy. This information helps researchers explain why immunotherapy works for some patients and not others. These archetypes increase information needed by physicians to appropriately treat the cancer tumors with the right immunotherapy, thereby significantly improving patient outcomes. Find more information here.

HPV Vaccine Saves Lives

New data confirms that the vaccine is already saving lives. The number of cervical cancer cases and deaths among American women dropped after the HPV vaccine was introduced in 2006, according to a November 2021 study in the Journal of the American Medical Association, reports mskcc.org. While this study speaks for itself, there are still many people afraid to get this vaccine for their children. HPV is a common sexually transmitted infection with very severe consequences to the body. There is an increase in throat and neck cancer caused by HPV, this has greatly affected both men and women. Physicians want to emphasize that this vaccine does not promote sexual activity, this vaccine saves lives. This simple vaccine can save the lives of many people and prevent cancer caused by HPV from ever occurring. Find more information here.

December 2021 Notable News

If you are like pretty much everyone in the world, you are tired of hearing about viruses, but there is a type of virus that you’ll be glad to learn about. You’ll also be glad to learn that blood tests are detecting cancer, immune cells are communicating with each other, and researchers are taking steps to reduce disparities in healthcare. You may not care to learn that there is yet another link between obesity and cancer, but there is, and that probably doesn’t come as a surprise at this point.

A study in Australia shows that obesity could lead to 10,000 cases of thyroid cancer in the next ten years, reports medicalxpress.com. The study found that one in five future thyroid cancers in the future will be linked to obesity levels today. The study shows the importance of preventing obesity in order to prevent cancer. The findings are especially troubling because the occurrence of obesity has doubled in Australia over the last 20 years. Obesity has been called a causal risk factor for thyroid cancer. Learn more about the study here.

Researchers have developed a new tool for determining the risk of breast cancer in black women in the United States, reports cancer.gov. Black women are usually younger when diagnosed and are more likely to be diagnosed with aggressive or advanced forms of breast cancer. Black women are also more likely to die from breast cancer. The tool, called the Black Women’s Health Study Breast Cancer Risk Calculator, is an online questionnaire that uses information about a woman’s medical, reproductive, and family history. The new screening tool is a step toward reducing the disparities in care for black women. Learn more about the risk calculator here.

Scientists have discovered how immune system cells communicate with each other to identify and eliminate tumors, reports sciencedaily.com. The information could help improve the number of patients who are able to benefit from immune therapies and could lead to the development of vaccines that could increase the survival rate for several cancers. Learn more about the findings and how the cells communicate with each other here.

A California company has developed a simple blood test that could detect up to 50 different kinds of cancer, reports webmd.com. The test, called Galleri, can even reportedly detect pancreatic, ovarian, and esophageal cancers, which are generally hard-to-detect. The test detects whether cancer signals were or were not detected and could lead to early detection of cancers. The test does not diagnose cancer and is not meant to replace regular recommended screenings but could help detect cancers that don’t have screening tests. The test doesn’t have full Food and Drug Administration (FDA) approval yet, and it’s meant for people at high risk for cancer. Patients can expect to pay $950 for the test which isn’t covered by insurance. Learn more about the Galleri test here.

Believe it or not, some viruses can help to fight diseases like cancer, reports sciencedaily.com. Oncolytic viruses are able to target and destroy cancer cells all while leaving healthy cells alone. Viruses outnumber all other life forms combined, and they infect every form of cellular life. The oncolytic viruses are known as specialists in that they are selective in the type of organisms they infect, and because they kill cancer cells and don’t harm normal cells, they could provide a key to new cancer therapies. Learn more about the potential cancer fighting viruses here.

Let’s hope that in 2022 the viruses that are making headlines are the cancer-fighting kind. Wishing you health, peace and hope in 2022 and beyond. Happy New Year.

November 2021 Notable News

Cancer research has come a long way in the last half century. Each month there is an amazing amount of new knowledge. There’s new information this month about childhood cancer, prostate cancer, pancreatic cancer, and a couple of vaccines. The research and advances we learn about each month are due in large part to the programs and systems that resulted from the National Cancer Act of 1971.

National Cancer Act of 1971

Fifty years ago, a few days before Christmas, President Richard Nixon signed the National Cancer Act of 1971, and the National Cancer Institute (NCI) is commemorating the anniversary at cancer.gov. The act established networks of cancer centers, clinical trials, data collection systems, and advanced research. As an amendment to the Public Health Service Act of 1944, by signing the act, Nixon declared a war on cancer. The bill expanded the authority of the director of the NCI and made possible many of the present-day advances in cancer research. Learn more about the National Cancer Act of 1971 and the impact it has had over the past 50 years here.

HPV Vaccine

One of the accomplishments noted by the NCI is the HPV vaccine. The vaccine for the human papillomavirus (HPV) is reducing the number of cervical cancer cases by almost 90 percent, says bbc.com. Almost all cervical cancer cases are caused by HPV, and cervical cancer is the fourth most common cancer in women worldwide. More than 100 countries are using the vaccine to help in the World Health Organization’s goal to eliminate cervical cancer. With such positive results in the United Kingdom, the hope is that the vaccine will have an even bigger impact in lower income countries. Read more here.

Covid-19 Vaccines

Covid-19 vaccines are safe and effective for most cancer patients, reports usnews.com. In a study that included more than 1,000 vaccinated cancer patients, researchers found that the vaccines were effective in protecting cancer patients from severe Covid-19. Patients who had been treated with chemotherapy, bone marrow transplants, or corticosteroids had a weaker immune response, but still benefited from the vaccine’s protection. Cancer patients had similar side effects as healthy vaccine recipients. Get more information here.

Pancreatic Cancer Detection

Researchers have identified two additional symptoms of pancreatic cancer that could help with earlier detection of the disease, reports webmd.com. The newly identified symptoms are feeling thirsty and having dark urine, and they are associated with the most common type of pancreatic cancer. Other symptoms include problems swallowing, diarrhea, vomiting, weight loss, abdominal swelling, tiredness, constipation, back pain, itching, loss of appetite, change in bowel habits, indigestion, abdominal pain, abdominal mass, nausea, flatulence, heartburn, and fever. Patients can have symptoms for up to a year before diagnosis. Get more information here.

Gut Microbiome and Prostate Cancer

A new study shows that there might be a link between the gut microbiome and deadly prostate cancer, reports medicalnewstoday.com. Researchers analyzed different metabolites in the blood serum of study participants and found a connection between aggressive prostate cancer and three of the metabolites. The metabolites, phenylacetylglutamine, choline, and betaine, are either produced by the gut or found in some foods. The metabolites are mostly found in meat and animal products, but also in beans, nuts, and diet sodas with aspartame. Men with high levels of choline or betaine were two times more likely to die of prostate cancer, and men with high levels of phenylacetylglutamine were 2.5 times more likely to die of prostate cancer. Learn more about the study here.

Childhood Cancer Survivors

Childhood cancer survivors tend to have higher risk of lifelong health problems, reports medicalxpress.com. A new study shows that the type of cancer and how the cancer was treated can affect the type of health issues survivors will have later in life. Researchers found that people who were treated with chemotherapy and radiation were most likely to experience later health problems. The lowest risk was for people who were treated only with surgery. Researchers say the long-term health effects should be considered when discussing treatment options for young people with cancer. Learn more about the study and watch an animated video that explains the study in an easy-to-understand manner here.

Here’s hoping that we will have more preventive vaccines and life-saving measures before the passing of the next 50 years.

October 2021 Notable News

It’s important to keep things in perspective, especially when there is a lot of information coming at you, and there is a lot of information this month. From unwarranted vaccine concerns and real concerns about fighter pilots to potential new therapies involving CBD oil, anti-nausea meds and immunotherapies, it’s a lot to take in. The most important take away is to make sure you exercise and make sure you know your cancer risks and when you should get your screenings.

Breast Cancer Screening

Black women may want to consider starting mammograms at age 40 rather than age 50, says sciencedaily.com. New information shows that breast cancer deaths in black women could be reduced by 57 percent when screening is done every other year beginning at age 40. The study was done as part of an effort to develop equitable health recommendations for black women who tend to have higher rates of aggressive cancers at younger ages than white women. Learn more here.

Preventing Cancer with Activity

Americans could be preventing more than 46,000 cancer cases each year, reports medicalxpress.com. New data shows that physical inactivity, especially in women, led to three percent of all cancer cases in adults aged 30 and older. While meeting the recommended guidelines of five hours per week of moderate intensity activity could prevent those cancer cases, researchers note that there are often obstacles in the way of people meeting exercise requirements such as access to safe places to exercise, childcare costs, and long working hours. Learn more here.

Immunotherapy

Researchers may have discovered a new way for immunotherapies to be used against more cancers, reports mit.edu. With the new method, researchers remove tumor cells from the body and treat them with chemotherapy. They then put the cells back in the tumor and administer drugs that activate T cells. That combination seems to be the trick to awaken the immune system. Researchers found that cells that were injured by the chemotherapy were more successful at triggering the immune system than dead cells were. Learn more about this promising new immunotherapy method here.

Dexamethasone Benefits

An anti-nausea drug could be the key to better short-term survival for patients who have surgery for some types of cancer, reports usnews.com. Researchers found that patients who received dexamethasone were about one-third less likely to die in the 90 days following their surgery. In order to prove the findings, clinical trials will need to be done. Learn more about dexamethasone and it’s potential to increase patient survival here.

Lung Cancer and CBD

A case study reported in medicalnewstoday.com showed that a lung cancer patient who took CBD oil showed a reduction in her tumor. CBD oil is a concentrated extract of cannabis leaves or flowers which is often used by cancer patients to treat pain, and the side effects of chemotherapy such as nausea and vomiting. The female patient, located in the United Kingdom, was in her 80s and smoked more than a pack of cigarettes a week before and after her diagnosis, and did not change her diet or lifestyle while she was being monitored. During a two-and-a-half-year period, her scans showed a progressive decrease in her tumor. Learn more about the case study here.

HPV Vaccine

Parents are expressing concerns about the safety of the HPV vaccines despite 15 years of evidence that they are safe and effective, reports cancer.gov. The HPV vaccine protects against cancers caused by the human papillomavirus and is recommend for 11- and 12-year-olds, but the study shows that the number of parents who declined the vaccine for their children due to safety concerns nearly doubled between 2015 and 2018. However, during the same time period the reports of serious complications from the vaccine were rare. Researchers suspect that social media use is a factor in the increased doubts about the vaccines. Find our more here.

Fighter Pilots and Cancer

United States Air Force Fighter Pilots and crew members are more likely to get some cancers than other members of the Air Force, reports defenseone.com. A comprehensive study among pilots and crew of fighter aircraft found that they were 29 percent more likely to be diagnosed with testicular cancer, 24 percent more likely to be diagnosed with melanoma, and 23 percent more likely to be diagnosed with prostate cancer. Researchers are encouraging fighter aviators to discuss the study and their potential cancer risks with their care providers. Get more information about the study here.

Check out nwaonline.com for a really nicely written perspective about celebrating anniversaries from a ten-year cancer survivor here.

September 2021 Notable News

A big yellow duck is raising awareness by having an adventure, researchers are becoming more aware of how cholesterol might affect cancer, and quitting smoking is always a good idea. A better breast cancer treatment and vaccines could be on the way for cancer patients, and fruit flies may be the key to longer lifespans.

Fruit Flies and Cancer

Researchers are learning a new anti-cancer strategy from studying fruit flies, reports technologynetworks.com. The research shows that, rather than trying to destroy tumors, treatments that attack destructive cancer chemicals could lead to improved health and survival rates. Researchers discovered that the tumors in fruit flies release a chemical, called interleukin-6 (IL-6), that weakens the barrier between the brain and the bloodstream and allows the bloodstream and brain environments to mix. The same chemical was found in mice and researchers were able to extend the lifespan of both the mice and the fruit flies by blocking the IL-6 impact on the blood-brain barrier. If researchers are able to find a drug that blocks the effect of IL-6 on the blood-brain barrier, it could potentially prolong the lives of cancer patients. Learn more about the fruit fly research here.

COVID-19 Booster Shot for Blood Cancer Patients

Some blood cancer patients could benefit from a Covid-19 booster shot, reports usnews.com. A study showed that more than half of the patients with B-cell blood cancers, who did not make antibodies after the first two Covid-19 vaccine shots, had a better result in making antibodies after the third booster shot. Blood cancer patients with questions about covid-19 vaccinations should consult their doctors. Get more information here.

Cancer Vaccines

Researchers have found some promising results studying the use of cancer vaccines, reports news.mit.edu. Experimental studies have helped to identify cancer proteins that, when vaccinated against, can potentially increase the body’s own immune response by waking up T cells to target the proteins. Over the past decade, scientists have been exploring cancer vaccines as a way for the body’s immune system to fight cancer. Learn more here

Breast Cancer Treatment

There is good news in breast cancer treatment, reports abcnews.go.com. New data shows that the drug ENHERTU worked better than the current treatment for HER-2 positive breast cancer, which is currently incurable. ENHERTU was more successful at reducing tumor size and keeping the patient alive longer. The results suggest that ENHERTU could become a first-line treatment for breast cancer and researchers are investigating to see if they have similar results using ENHERTU to treat other cancers such as stomach and lung cancers. Read more here

Lung Cancer and Smoking

It’s never too late to quit smoking, says cancer.gov. A new study shows that quitting smoking after being diagnosed with early-stage lung cancer could help people live longer and could also delay a return of the cancer. In the study, the people who quit smoking lived a median of 22 months longer than those who did not quit. Learn more about the findings here

There is also new information from cancer.gov about lung cancer among people with no history of smoking. A study has found that most of the tumors are caused by the mutations of natural processes in the body. The study also identified three subtypes of cancers among never smokers. The findings could help researchers develop better treatments for these types of lung cancer. Learn more here.

High Cholesterol and Cancer

Scientists are beginning to understand why there may be a link between high cholesterol and cancer, reports medicalnewstoday.com. Researchers have found that high cholesterol levels may help make cancer cells resistant to death. Using cell lines and mice models, researchers found that exposure to a derivative of cholesterol, known as 27HC, led to the growth of tumors and prevented the process of natural cell death in cancer cells. Understanding the link between cholesterol and cancer could lead to creating better cancer treatments. Find more information here.

Mr. Vanderquack

There are many ways to spread cancer awareness, but perhaps none more fun than a 20-inch duck in a Jeep traveling the country. The duck, Mr. Vanderquack, has a GPS tracker and is traveling to all 50 states in an effort to raise money for St. Jude Children’s Cancer Research, says wate.com. Thousands of Jeep owners have volunteered to drive Mr. Vanderquack around the country where he will visit over 650 cities. Mr. Vanderquack’s journey began in early September and is expected to take three months. You can follow the journey and sign up for email updates at mrvanderquack.com or on Instagram @mrvanderquack. Mr. Vanderquack’s adventure has already raised more than $20,000. Get more information here

August 2021 Notable News

The news this month is a little nutty! Actually, it’s a little peanutty! It turns out that eating peanuts could cause cancer to spread but drinking milk could save young people from developing colon cancer. Widowers are more likely to have advanced prostate cancer, and having a positive attitude isn’t necessarily a requirement for surviving cancer. All that and a glimpse into the state of cancer rates across the globe.

Global State of Cancer

A chart detailing the cancer survival, incidence, and death rates of several countries provides information about the global state of cancer, says medicalnewstoday.com. The lowest cancer rates were found in India, which also had the lowest cancer death rates. Doctors in India believe that prevention and education, service delivery, and research should all be equal in cancer care. The United States has the highest cancer rate, but possibly because of the screening tests that detect cancer earlier and more successfully than in other countries. However, the US also has a prevalence of cancer risk factors, such as obesity, that could be contributing to the high incidence of cancer. China has the highest cancer mortality rate. Learn more about the state of cancer in other countries here.

Potential Cause of Metastasis

A recent study shows that cancer patients who eat a lot of peanuts could have an increased risk of metastasis, reports sciencedaily.com. The study showed that, after eating peanuts, a carbohydrate-binding protein called peanut agglutinin (PNA) enters the blood stream. The PNA interacts with blood vascular wall cells which then leads to the production of cytokines, molecules that are known to cause cancer to spread. Another study showed that PNA binds to a sugar chain that is associated with cancer cells and that it could lead to the cancer cells being stickier and easier to attach to blood vessels. While more research needs to be done, patients may want to use caution when it comes to eating large quantities of peanuts. Find more information

here.

Vitamin D Benefits

Vitamin D could help younger adults protect themselves against colon cancer, reports usnews.com. Researchers have learned that the overall incidences of colon cancer are decreasing, but among younger adults, colon cancer is on the rise. The increase in cases seems to be linked with a decline in eating foods full of vitamin D, such as fish, mushrooms, eggs, and milk. The study found that young people could reduce their risk of getting colon cancer at an early age by about 50 percent if they consumed 300 IU of vitamin D each day, which is the equivalent of about three glasses of milk. The study is the first to make the connection between vitamin D levels and the rising rates of colon cancer in the younger population. Read more about the connection here.

Widowers and Prostate Cancer

Researchers found that widowers are more likely to be diagnosed with advanced prostate cancer, reports medicalxpress.com. Widowers tend to be diagnosed later than married men or men in a relationship, when the cancer has reached advanced stages and has spread into other areas of the body. Studies have shown that people living with a partner have a healthier lifestyle and are more likely to be encouraged to see a doctor when symptoms appear. For better health outcomes, widowers can turn to family and friends for support and be sure to have regular medical checkups. Learn more here.

Power of Positivity

Some people say that the secret to beating cancer is all about having a positive attitude, but as 20-year cancer survivor Caitlin Flanagan points out in theatlantic.com, sometimes it’s hard to feel positive about a cancer diagnosis and treatment. Read this great piece about why the power of positive thinking may not be a requirement to survive cancer here.


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July 2021 Notable News

In case you haven’t heard, there’s a sunscreen recall, but that may not be the only common household product that could contain cancer-causing chemicals. New research has found a clue to understanding metastasis and hope for treating pancreatic cancer, and it’s time for Americans to admit that consuming alcohol is putting them at greater risk for developing several types of cancer.

Even though fewer than one in three Americans equate drinking alcohol with getting cancer, a recent study links alcohol consumption to more than 740,000 new cases of cancer, reports advisory.com. The three most common alcohol-related cancers are esophageal, liver and breast, but the study also found that mouth, larynx, colon, and rectum cancers are related to alcohol consumption. Cancer risk increased with the amount of alcohol consumed, but even moderate drinking (two or fewer drinks per day) was linked to 14 percent of the alcohol-related cancers. Men may have a higher risk factor as they made up 75 percent of the cancer cases related to alcohol. There are several reasons alcohol consumption is linked to cancer including the way alcohol breaks down in the body. Ethanol, which is the alcohol in beer, wine, and liquor, breaks down into a known carcinogen called acetaldehyde. Other factors are alcohol’s ability to increase hormone levels and to hinder nutrient absorption by the body. Learn more about the link between alcohol consumption and cancer here and here.

A healthy protein in a once-overlooked tiny cell component called an intracellular nanovesicle (INV) may be a clue in explaining how it’s possible for some cancers to metastasize and form secondary tumors, reports medicalxpress.com. The protein, named Tumor Protein D54 (TPD54), is involved in the movement of cells. Researchers found that when higher levels of TPD54 were present cell movement increased, and when there was less TPD54 the cells moved less. Increased levels of the protein are associated with some breast cancers that tend to metastasize indicating that TPD54 plays a role in movement of the cancer cells. However, targeting TPD54 to treat cancer is not ideal as the protein is important for a number of normal cell processes including wound healing and immune response. The discovery of the TPD54 role in cell movement along with more study of the INVs and their function as couriers within a cell, could lead to further understanding of metastasis of cancer cells. Find more information here.

A clinical trial for a new pancreatic cancer treatment is showing positive results, reports biospace.com. The ongoing trial is being conducted by Lantern Pharma for the drug candidate LP-184. So far, the preclinical data showed that pancreatic tumors in mouse models shrank with a promising 90 percent efficacy over eight weeks. In comparison, a control group of untreated mice showed tumor growth over the same period. In addition, researchers saw a significant reduction of cancer cells and cancer cell growth in other models. Further study of LP-184 is planned. Learn more here.

Exposure to household chemicals could increase the risk for breast cancer, reports medicalnewstoday.com and studyfinds.org. Researchers say there could be as many as 300 toxic chemicals in common household items such as processed foods, make up, hair products, and furniture. Many household items contain chemicals known as endocrine disrupting inhibitors, and researchers say we should be concerned about our exposure to these chemicals which can alter the hormones that affect breast cancer. While the impact of many of the chemicals is still unknown, there is evidence that some of the chemicals make cells in breast tissue produce more estrogen and progesterone, which both have a known link to breast cancer. Learn more here and here.

Neutrogena, Aveeno, and CVS Health have voluntarily recalled some of their sunscreens or after sun products, reports cnn.com. The sunscreens were found to have been contaminated with benzene, a chemical that increases the risk of developing leukemia and other blood disorders. The recalled products are all batches or lots of Neutrogena Beach Defense aerosol, Neutrogena Cool Dry Sport aerosol, Neutrogena Invisible Daily defense aerosol, Neutrogena Ultra Sheer aerosol, and Aveeno Protect + Refresh aerosol. All recalled Neutrogena and Aveeno sunscreens can be found here, and customers can request a refund by completing the form here, or calling 1-800-458-1673. CVS also stopped selling CVS Health After Sun Aloe Vera and CVS Health After Sun Aloe Vera Spray after the Neutrogena and Aveeno products were recalled. Experts say the recall is not a reason for people to stop using sunscreen as the majority of sunscreens on the market do not contain benzene and successfully protect against skin cancers. An independent lab tested sunscreens and found that most of them did not contain benzene. Learn more about the recalled products and benzene here.


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Notable News June 2021

You might want to put on a fresh pot of coffee for this one. Lemon Frost geckos, genetically engineered mice, and American Lobsters have a lot to teach us about cancer; it looks like it’s past time to cut down on the amount of red meat we eat; there could be a new treatment for metastatic prostate cancer; and there are some clinical trials under way for cancer vaccines using the same technology as the Covid-19 vaccines. We’ll be hearing a lot about mRNA in the coming years.

The mRNA vaccine technology used to create the Covid-19 vaccines is the result of nearly two decades of research by scientists in many fields, including cancer, and now researchers are hoping to apply the technology to cancer vaccines, reports medicalxpress.com. The mRNA technology is flexible and versatile, and that makes it ideal for treating many diseases. For example, in Covid-19 vaccines, the mRNA works as a protective measure fighting off invading cells, but as a cancer vaccine, mRNA works more as a treatment. It works by motivating T cells to kill cancer cells, similar to how immunotherapy works. Like immunotherapy, the mRNA vaccines would need to be personalized to each patient, and that could be a challenge in the development of the vaccines. Despite any challenges, clinical trials for mRNA cancer vaccines are already underway. Learn more about the exciting technology here.

In addition to the prospect of new vaccines, there could be a breakthrough in treating prostate cancer, reports Memorial Sloan Kettering Cancer Center at mskcc.org. A therapy called Lu-PSMA-617 has been developed to attach to and kill the cancer cell using radiation. The treatment works on cancer cells that have been resistant to other therapies, as is often the case in prostate cancer after it has spread. Lu-PSMA-617 recently received Breakthrough Therapy designation from the Food and Drug Administration (FDA) which will help speed up the development and review of the therapy. Learn more about the promising treatment here.

What we eat and drink continues to affect our cancer risk. Researchers may have identified the connection between diets rich in red meat and colorectal cancer, reports medicalxpress.com. While experts have long advised against eating red meat to prevent colorectal cancer, there was no definite proof of a connection between red meat consumption and colorectal cancer. However, researchers have now discovered that there are specific patterns of DNA damage, called alkylation, caused by eating a lot of red meat. Learn more about the findings here.

While you are avoiding red meat, you can fill up on coffee. Drinking three to four cups of coffee a day could reduce your risk of liver cancer and other liver diseases, reports usatoday.com. The authors of a study in the United Kingdom say that they can’t definitively prove that coffee lowers the risk of liver disease, but there was a noticeable reduction in liver-related disease among coffee drinkers. Researchers advised that people should follow healthy practices like eating well and exercising in addition to drinking coffee. Also, don’t overdo it. The study found that any more than three to four cups a day did not provide additional benefits. Learn more here.

We continue to have a lot to learn from the animal kingdom. A gecko named Mr. Frosty could be the key to finding treatment for skin cancer, reports sciencenews.org. Mr. Frosty is a Lemon Frost gecko, a type particularly prone to tumors. Researchers collected DNA from Mr. Frosty and many other lizards and were able to use the data to link tumor growth to a gene called SPINT1. The gene has also been linked to melanoma in humans, which could mean that Lemon Frost geckos could be used to research treatments for skin cancer. Learn more about Mr. Frosty here.

Genetically engineered mice provide a great research model for humans. Scientists have developed a new technique to determine which cancer research models are the most similar to cancer cells that grow in humans, reports sciencedaily.com, and the most similar are genetically engineered mice and 3D balls of human tissue called tumoroids. The technique, called CancerCellNet, is computer based and compares RNA sequences of a research model with data from a cancer genome atlas to determine how well the two match. The mice and the tumoroids were the closest match in four out of every five tumor types tested. Researchers found that human cancer cells grown in culture dishes are the least similar. Learn more here.

Lobsters seem to age better than anything on the planet. Scientists are studying lobsters to see if their longevity and ability to stay mostly cancer free can provide answers for humans about aging and disease prevention, reports sciencemag.org. Lobsters live up to 100 years in the wild, do not lose strength or fertility with age, and they very rarely get cancer. While the complete set of lobster genes is so long that researchers are still uncovering it, they are hopeful that more research could provide insight into how lobsters stay cancer free and how humans may be able to benefit from the information. Learn more here.


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May 2021 Notable News

The new magic number for colorectal screenings is 45 not 50, parking fees are affecting cancer care, and there are a lot of promising developments regarding potential vaccines, lung cancer treatments and breast cancer screenings, but all the advances in cancer care are not equally available to everyone, and a cancer alliance has issued a call to action.

The disparities in cancer care are profound and widespread, says the Community Oncology Alliance (COA) in a statement posted by journalofclinicalpathways.com. The COA statement notes that an estimated 34 percent of cancer deaths among adults between the ages of 25 to 74 could be prevented if socioeconomic disparities were eliminated. People in groups defined by such things as race and ethnicity, disability, gender identity, income, education, national origin, and geographic location are likely to experience disparities in access to screening, access to care, and ability to pay for care. Read the full COA statement and their call to action here.

Cancer care disparity is also evident in states where fewer people qualify for Medicaid, where, due to lower income eligibility limits, cancer patients have shorter long-term survival rates, reports cancernetwork.com. Medicaid eligibility is not the same in every state. Some states set Medicaid eligibility incomes higher than others, meaning that in order to qualify for Medicaid, income levels have to be at or below the income eligibility level set by each specific state. Texas, for example, has a low income eligibility requirement, so fewer people qualify for Medicaid. A recent study showed that in areas where Medicaid eligibility limits are the lowest, the length of survival was shorter than in the states with high eligibility limits. The study assessed the relationship between state Medicaid income eligibility limits and long-term survival of cancer patients by using the data of 1.5 million adults from the National Cancer Database who were newly diagnosed with 17 common cancers. Researchers noted the study highlights the critical need for equitable care because people who are uninsured are less likely to have regular screenings and are unlikely to start or complete cancer care. Learn more here.

Believe it or not, parking might be affecting quality of cancer care. As pbs.org reports, high parking fees are weighing heavily on many cancer patients and their caregivers, and the negative effects of the cost of parking for cancer treatments are gaining attention from oncology researchers and hospital administrators. Some of the best cancer treatment centers are located where parking is a premium and patients can end up paying up to $40 a day in parking fees. It’s an additional, out-of-pocket expense that no one expects when they get a cancer diagnosis, and it can really add up. A study revealed that some patients pay $1,680 in parking fees during cancer treatment. One patient revealed that he opted not to participate in a clinical trial because he couldn’t afford the cost of parking. Read more about this hot topic here.

While the inequities in care are discouraging, the advances in screenings and treatments continue to be encouraging. There is new hope for people with early-stage lung cancer in the form of an immunotherapy drug, says webmd.com. The drug, an immune checkpoint inhibitor called atezolizumab, is the first to significantly reduce the risk of cancer recurrence or death in people with stage 11 or 111A non-small cell lung cancer. The risk is reduced by 34 percent compared to a 16 percent reduction from currently used chemotherapy. While the findings are promising, the drug can have some serious, life-threatening side effects. Find more information here.

An updated breast cancer screening may be on the way with the development of a new biosensor to help detect early-stage breast, reports medicalxpress.com. The biosensor, developed in Spain, helps detect cancer through a blood test, and it is easy to use, inexpensive, and yields results in 30 to 60 minutes. Learn more about how the biosensor test works here.

The screening methods for colorectal cancer remain the same, but the timeline is changing. Colorectal cancer is the third leading cause of cancer deaths in the United States and experts are now recommending that routine screening start five years earlier, reports npr.org. The U.S. Preventive Services Task Force, an independent volunteer panel of national experts, now says that screening should begin at age 45 instead of age 50. The recommendation is expected to save lives and give more people access to the screening tests. Learn more here.

The earlier screenings combined with a potential vaccine could put us on the right path to knocking colorectal cancer out of its third-place ranking for cancer deaths. Researchers at MD Anderson Cancer Center are using the mRNA technology that was used to create the COVID-19 vaccines to create a vaccine for stage two and stage three colon cancers, reports KHOU 11 News Houston, khou.com. Originally developed many years ago to treat cancer, mRNA vaccines can be personalized to each patient, and through clinical trials this summer, researchers will test if the vaccines can eradicate microscopic cancer cells left behind in colon cancer patients who have had tumors surgically removed. Eradicating the remaining cancer cells will prohibit the cancer from returning. Researchers say the vaccines can be applied to other cancers as well. Watch the KHOU 11 report and learn more about how the mRNA vaccines work here.

There has been a drop in cervical cancers thanks to screening and the HPV vaccine, but other cancers caused by the human papillomavirus are on the rise, reports apnews.com. HPV is the most common sexually transmitted virus and while most infections have no symptoms and go away without treatment, each year about 35,900 of the infections develop into cancer. It can take decades for an HPV infection to develop into cancer, which might explain the rise in some cancers. Experts say that the cancers we’re seeing now could be a result of the sexual practices of Baby Boomers in the late 1960s, 70s, and 80s. Oral and throat cancers have increased the most in men, and anal cancer and a rare rectal cancer have increased the most in women. Young women, who would have been the first to get the HPV vaccine when it made its debut in 2006, saw the biggest drop in cervical cancer cases. Find more information here.