Myeloproliferative neoplasms (MPNs) are a closely related group of progressive blood cancers in which the bone marrow typically overproduces one of the mature blood elements. Other shared features include tendencies toward blood clotting/bleeding, organ enlargement, bone marrow scarring (fibrosis) and a possibility of transformation.

There are three blood cancer types that are categorized as “classic” MPNs: Primary Myelofibrosis (MF), Essential Thrombocythemia (ET) and Polycythemia Vera (PV).

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