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Waldenström Macroglobulinemia Diagnosis & Testing

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Diagnosis & Testing
How Is Waldenström Macroglobulinemia Diagnosed?

Diagnosing Waldenström macroglobulinemia (WM) involves a series of evaluations, including a physical exam, a review of your medical history, and specialized blood and bone marrow tests. 

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Expert Advice for Newly Diagnosed Waldenström Macroglobulinemia (WM) Patients

Waldenström Macroglobulinemia Staging
Unlike many other lymphomas, Waldenström macroglobulinemia does not follow a traditional staging system. Instead, healthcare providers assess disease progression based on symptoms, IgM levels, and bone marrow involvement.
Essential Testing

A definitive diagnosis of WM requires several key tests, including:

  • Blood Tests: determine the types and amounts of antibodies in your blood
  • Bone Marrow Aspiration and Biopsy: Confirms the presence of abnormal lymphoplasmacytic cells
  • Genetic Testing: Identifies MYD88 and CXCR4 mutations, which can influence treatment decisions
  • Imaging Tests: Such as a CT or PET scan to determine if the cancer has spread beyond the bone marrow
Waldenström Macroglobulinemia Diagnosis & Testing Programs
These programs help you understand your diagnosis, and how testing can identify the stage of disease and predict how well treatment may work for you.

Provides actionable advice and downloadable materials to help you communicate clearly and effectively with your WM healthcare team.​

Topics:

  • Understanding Waldenström Macroglobulinemia 
  • Waldenström Macroglobulinemia Treatment Approaches  
  • Tips for Waldenström Macroglobulinemia Patient Self-Advocacy  
  • Planning Your Waldenström Macroglobulinemia Doctor’s Office Visit 
  • Pro-Active Waldenström Macroglobulinemia Patient Resources 

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