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Myeloproliferative Neoplasms Diagnosis & Testing

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Diagnosis & Testing
How Are Myeloproliferative Neoplasms Diagnosed?

Diagnosing MPNs begins with blood tests, followed by bone marrow biopsies and imaging, if needed, to confirm the diagnosis and assess disease progression.

Myeloproliferative Neoplasms Types

The three types of MPNs include:

  • Essential Thrombocythemia (ET): An overproduction of platelets
  • Polycythemia Vera (PV): A higher-than-expected red blood cell mass (hematocrit)
  • Myelofibrosis (MF): An advanced bone marrow failure state with scarring or fibrosis of the bone marrow

Related Links

Myeloproliferative Neoplasms Defined: What Are ET, PV, and MF?

Understanding High-Risk vs Low-Risk Disease in ET, PV & MF

Essential Testing
  • Complete Blood Count (CBC): Checks for abnormal blood cell counts.
  • Bone Marrow Biopsy: Assesses bone marrow function and fibrosis.
  • Biomarker Testing: Laboratory testing that identifies certain gene mutations, proteins, chromosomal abnormalities, and/or other molecular changes that are unique to an individual’s disease. 

Related Links

Which Tests Do You Need Following an MPN Diagnosis?

An Expert Shares Key Steps to Take Following an MPN Diagnosis

Myeloproliferative Neoplasms Diagnosis & Testing Programs
These programs help you understand your diagnosis, and how testing can identify the stage of disease and predict how well treatment may work for you.

Tools to help you feel activated and connect with resources to overcome barriers to accessing care.

Topics:

  • Navigating MPN Care 
  • Advances in MPN Therapies 
  • [ACT]IVATED MPN Patient Vignettes
  • [ACT]IVATED MPN Resources 

Provides the knowledge to actively participate in care decisions and understand support resources available.

Topics:

  • Tips and Advice for Myelofibrosis Patient Self-Advocacy 
  • Understanding Myelofibrosis Treatments and Treatment Decisions 
  • ELEVATE Myelofibrosis Resources 

Provides tools and actions for shared decision making and tips for navigating MPN treatment decisions.

Topics:

  • Understanding Myeloproliferative Neoplasms 
  • Myeloproliferative Neoplasms Treatment Options 

Will help you understand the importance of essential biomarker testing before key decisions are made in your care—including following a reoccurrence.​​

Topics:

  • Understanding MPNs and Testing 
  • MPN Treatment Decisions 
  • INSIST! MPN Resources 

Brought to you by and for patient advocates to assist you on your path to empowerment and better care.

Topics:

  • Understanding MPN Lab Tests and Monitoring 
  • MPN Treatment Decisions 
  • MPN Clinical Trials and Research 
  • Lifestyle and Mindfulness Tools for People with an MPN 

Provides actionable advice and downloadable materials to help you communicate clearly and effectively with your MPN healthcare team.

Topics:

  • Understanding MPN and MPN Subtypes 
  • MPN Treatment Types and Treatment Decisions 
  • Planning for Your MPN Doctor’s Office Visit 
  • Pro-Active MPN Patient Toolkit Resources 

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