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Testicular Cancer

Testicular cancer is a cancer that starts in the testicles (also called testes), which are part of the male reproductive system. The testicles are located in the scrotum (the pouch of skin below the penis) and are responsible for making sperm and testosterone.

Testicular cancer is rare, but it’s the most common cancer in young men aged 15 to 35. Most cases are highly treatable and early detection makes a big difference. The most common symptom is a painless lump or swelling in one testicle.

Doctors use a physical exam, ultrasound, blood tests (tumor markers), and imaging scans to diagnose and stage testicular cancer. Treatment usually involves surgery, and may also include radiation or chemotherapy, depending on the type and stage.

Types of testicular cancer include:

  • Germ Cell Tumors: These make up about 95% of all testicular cancers and are divided into two main types:
    • Seminomas: These grow more slowly and usually affect men in their 30s or older. They respond well to radiation and chemotherapy.
    • Non-seminomas: These tend to grow more quickly and often occur in younger men. They include several subtypes:
      • Embryonal carcinoma
      • Yolk sac tumor
      • Choriocarcinoma
      • Teratoma

Sometimes, a tumor can contain both seminoma and non-seminoma cells.

  • Stromal Tumors: These are rare tumors that begin in the supportive or hormone-producing tissues of the testicle, such as:
    • Leydig cell tumors
    • Sertoli cell tumors
  • Secondary Testicular Cancers: These are cancers that have spread (metastasized) from another part of the body. They are rare and treated differently.

 

For more information about testicular cancer, please visit the organizations listed below.

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General Cancer Programs

PEN created these programs to help explain parts of the cancer journey.

Debunks myths about clinical trials and provides patients with knowledge and confidence to feel well-informed when discussing treatment options with their healthcare team

Topics:

  • The Basics: Understanding Clinical Trial Research
  • Understanding Common Misconceptions
  • Clinical Trial Safety
  • Clinical Trials 101 Resource Guides

As artificial intelligence (AI) reshapes oncology, DECODE empowers cancer patients and families with clear, practical insights into AI and other emerging healthcare technologies, breaking down how these innovations are transforming cancer care and helping them navigate AI-driven advancements with confidence.

Components:

  • Podcasts
  • Downloadable Resource Guides

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Aims to help you reduce risk, treat, and survive cancer by growing your confidence and teaching you the skills and benefits of making decisions with your healthcare team.

Helps women living with cancer understand the impact on their overall health, including fertility, hormones and sexual wellbeing while enabling informed conversations with their healthcare team about potential options and support.​

Information on completing cancer care with actionable steps to engage in key discussions and plan for life after treatment.

Topics:

  • Understanding Survivorship
  • Advice for Future and Follow-Up Care

Having cancer or caring for someone with cancer can feel really lonely and extremely isolating. We created PEN-Powered Activity Guides to help you cope, relax, and, hopefully, feel a little less overwhelmed. 

Focuses on wellness during cancer treatment and post cancer treatment.

Topics:

  • Lifestyle
  • Diet and Healthy Eating
  • Supportive Care

Advocacy program focusing on culturally competent whole-person healthcare, treating the whole-patient in tandem with existing care. 

What You Need to Know Before Choosing a Cancer Treatment

Advocacy program focusing on culturally competent whole-person healthcare, treating the whole-patient in tandem with existing care. 

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