Entries by Art Flatau

FLT3 Inhibitors for AML Update

Introduction Mutations in the FLT3 (fms-like tyrosine kinase 3) gene are the most common mutations seen in Acute Myeloid Leukemia (AML) patients. FLT3 mutations are seen in about 30% of […]

Olutasidenib for Relapsed or Refractory Acute Myeloid Leukemia with IDH1 Mutation

Introduction  Once again a new drug that was recently FDA approved for some Acute Myeloid Leukemia (AML) patients. Olutasidenib (brand name: Rezlidhia) was approved in December 2022 for AML patients […]

Omidubicel (Expanded Cord Blood) for use in Allogeneic Transplant

Introduction Umbilical Cord Blood (UCB) has been used as a source of stem cells in allogeneic (donor) transplants since the late 1980s. When doing a transplant using bone marrow (BM) […]

Rezafungin for the Treatment of Candidemia and Invasive Candidiasis in Adults

Introduction  I was the patient representative on the FDA Advisory Antimicrobial Drugs Advisory Committee (AMDAC) that met on January 24, 2023, to consider whether to recommend the approval of a […]

Quizartinib in FLT3-ITD-Positive AML

Introduction  I generally think of treatments for AML as old, meaning they were around when I was diagnosed in 1992, or new ones that were developed after that. In the […]

Ivosidenib and Azacitidine for IDH1-Mutated AML

There has been another significant advance in the treatment of Acute Myeloid Leukemia (AML) at least for the small subset of patients (6-10%) who have a mutation in one of […]

Naïve T-cell Depletion in Donor Blood Stem Cell Transplant Patients 

Introduction  T-cell depletion is a strategy to remove T-cells from bone marrow or peripheral stem cells taken from a donor before they are given to a patient. T-cell depletion (TCD) has […]

Low Testosterone in Cancer or Transplant Survivors

I was one of the authors (out of more than 50) of a review article on male specific late effects in stem cell transplant patients [1]. The article looked at […]

Introducing Art Flatau, AML Empowerment Lead

I have decided to try my hand at writing a regular blog.  I hope to write a post every month or so. This first post is something of an introduction.  […]