endometrial cancer treatment Archives

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Endometrial Cancer Treatment Options for Patients to Consider from Patient Empowerment Network on Vimeo.

What do endometrial cancer patients need to consider for treatment options? Expert Dr. Ebony Hoskins explains key factors that play into treatment decisions and recommended questions for patients to ask their doctor.

Dr. Ebony Hoskins is a board-certified gynecologic oncologist at MedStar Washington Hospital Center and assistant professor of Clinical Obstetrics and Gynecology at Georgetown University Medical Center.

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“…asking the right questions in terms of “How effective is this treatment that you’re recommending? Do you think it’s worth the side effects? Is my quality of life going to be affected? Can I still travel?”

Emerging Endometrial Cancer Treatments | Promising Data and Challenges

Related Resources:

What Endometrial Cancer Patients Should Know About Clinical Trials

What is the Role of Immunotherapy in Endometrial Cancer?

Transcript:

Mikki:

Dr. Hoskins, how do you work with your patients to make treatment decisions and what increase in treatment options, what should endometrial cancer patients consider when deciding on treatment?

Dr. Ebony Hoskins:

So I think this is a good question. In terms of patients up front, I think we follow kind of certain guidelines, if you will and providing standard of care and the first frontline therapy is pretty standard, right? In terms of advanced treatment, when patients recur and we have to look at alternate treatment therapies, I always look at the patient, I always look at what their medical problems are or any side effects. And, of course, the data to see how well are they going to do what side effects and quality of life?

There are numerous factors that are not just something looking in a book and say, “Okay, I’ll take A,” right? Like I think we have to look at all of that and make a decision with our patients over undergoing the side effects, the efficacy, all of these things that are in mind when we talk to patients. So my activation tip for patients would be being involved in the decision-making, asking the right questions in terms of “How effective is this treatment that you’re recommending? Do you think it’s worth the side effects? Is my quality of life going to be affected? Can I still travel?” Those are questions like, we want to live, right? And I don’t think anybody wants to be stuck every three weeks getting treatment or…so those are questions to ask in terms of like, quality of life. And so those are questions that I would recommend you ask your doctor when you’re deciding what treatments.

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Emerging Endometrial Cancer Treatments | Promising Data and Challenges

May 4, 2023/in EC Activated Expert, Endometrial Cancer, Endometrial Cancer Activated, Endometrial Cancer Newly Diagnosed, Endometrial Cancer Programs, Endometrial Cancer Treatment and Clinical Trials, Endometrial Cancer Video ND, Endometrial Cancer Video TC, GNYC Treatment and Clinical Trials, GYNC Newly Diagnosed, GYNC Video ND, GYNC Video TC, Gynecological Cancers /by Kara Rayburn

Emerging Endometrial Cancer Treatments | Promising Data and Challenges from Patient Empowerment Network on Vimeo.

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What is the latest in endometrial cancer treatment updates? Expert Dr. Ebony Hoskins shares updates from the RUBY study and one NRG study and provides advice for patients.

Dr. Ebony Hoskins is a board-certified gynecologic oncologist at MedStar Washington Hospital Center and assistant professor of Clinical Obstetrics and Gynecology at Georgetown University Medical Center.

[ACT]IVATION TIP

“…if someone’s diagnosed with endometrial cancer, ‘Am I a candidate for a clinical trial to be a part of this new frontier, if you will, for endometrial cancer?’”

Endometrial Cancer Treatment Options for Patients to Consider

Related Resources:

What Endometrial Cancer Patients Should Know About Clinical Trials

What is the Role of Immunotherapy in Endometrial Cancer?

Transcript:

Mikki:

Dr. Hoskins, what endometrial cancer data and studies coming out of major medical conferences are you most excited about? And can you speak to those kinks and challenges or promises of emerging treatments?

Dr. Ebony Hoskins:

Well, Mikki, I’m very excited. The SGO 2023 in Tampa, Florida, we had new data that came out from one of the NRG studies as well as another study called the RUBY Study. And both were looking at up-front carboplatin (Paraplatin) and paclitaxel (Abraxane) with the addition of immunotherapy. And we saw improved progression-free survival. So that means when the disease is no longer there, how long are patients living without it recurring, and that has increased. So this is a big deal.

And then one of the studies showed again, the data is still maturing so it’s not completely out there yet. So we still have to wait on it, but there may be improved overall survival. And that’s kind of one of the study goals that we always want to do is improve overall survival. So I’m excited about that. There was also some new data looking at whether up-front patients with advanced endometrial cancer, whether they are treated with systemic chemotherapy versus systemic chemotherapy and radiation.

And this is a long ongoing survival data that said, patients basically did equally well with just chemotherapy alone without the addition of radiation. So that I think is very interesting, because we use radiation and chemotherapy in patients with advanced endometrial cancer. That certainly doesn’t mean that it’s not an option, just means that it may need to be more tailored and discussed and discussed with our radiation oncology colleagues.

In terms of what the challenges are, I think immunotherapy is a game changer. But it’s also what I use in terms of second-line treatment. So now I’m using it up front. What happens if a patient recurs while on it? What am I going to do now? That’s my question. What am I going to do next? And I’m not too worried because there are new treatment options that are out. Again, they are not necessarily standard now, but they’re ongoing in clinical trials. So I’m not too worried. But definitely some questions that cross my mind. My activation tip for this for patients is if someone’s diagnosed with endometrial cancer, “Am I a candidate for a clinical trial to be a part of this new frontier, if you will, for endometrial cancer?”

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What Treatment Options Are Available for Advanced Endometrial Cancer?

May 4, 2023/in EC Activated Expert, Endometrial Cancer, Endometrial Cancer Activated, Endometrial Cancer Newly Diagnosed, Endometrial Cancer Programs, Endometrial Cancer Treatment and Clinical Trials, Endometrial Cancer Video ND, Endometrial Cancer Video TC, GNYC Treatment and Clinical Trials, GYNC Newly Diagnosed, GYNC Video ND, GYNC Video TC, Gynecological Cancers /by Kara Rayburn

What Treatment Options Are Available for Advanced Endometrial Cancer? from Patient Empowerment Network on Vimeo.

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What are the latest advanced endometrial cancer treatment options? Expert Dr. Ebony Hoskins shares updates about research advances and advice for newly diagnosed patients to be proactive in their care.

Dr. Ebony Hoskins is a board-certified gynecologic oncologist at MedStar Washington Hospital Center and assistant professor of Clinical Obstetrics and Gynecology at Georgetown University Medical Center.

[ACT]IVATION TIP

“…if a patient is newly diagnosed with endometrial cancer, is going in, knowing that we have more molecular markers, ‘Hey, are you going to send my tumor for next-generation sequencing, or are you going to be looking at the tumor for more information about targets that we could use for treatment?’

What Treatment Options and Factors Should Be Considered for Endometrial Cancer?

Related Resources:

Are Endometrial Cancer Outcomes Worse for Minority Patients

Are Endometrial Cancer Outcomes Worse for Underrepresented Patients?

How Can Endometrial Cancer Patients Advocate for Better Care?

Transcript:

Mikki:

Okay. Dr. Hoskins, fortunately, the endometrial cancer arsenal keeps expanding. What promising treatments are available to patients facing advanced endometrial cancer diagnosis?

Dr. Ebony Hoskins:

So, in recent years, we’ve had more research dollars into endometrial cancer that wasn’t there, say even five to 10 years ago. Some of the promising treatments that are coming about, are treatments that look at the molecular markers, meaning when we look at the tumor, and determining what proteins that are upregulated or down, now we have treatments that can more target, if you will, the specific cancer. So I think, these are definitely promising.

Other promising things that are occurring is that we are having more clinical trials that are offered for patients with advanced endometrial cancer that I know in my earlier years in practice or even in training, that just were not there. So I think this is a good time in the advancement in terms of endometrial cancer.

So my activation tip for this would be if a patient is newly diagnosed with endometrial cancer, is going in, knowing that we have more molecular markers, “Hey, are you going to send my tumor for next-generation sequencing, or are you going to be looking at the tumor for more information about targets that we could use for treatment?”

So those are questions that as a patient you can ask, because now these treatments are covered, and the testing is covered. And so we’re in a different realm than we were say, even five to 10 years ago.

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What Treatment Options and Factors Should Be Considered for Endometrial Cancer?

May 4, 2023/in EC Activated Expert, Endometrial Cancer, Endometrial Cancer Activated, Endometrial Cancer Newly Diagnosed, Endometrial Cancer Programs, Endometrial Cancer Treatment and Clinical Trials, Endometrial Cancer Video ND, Endometrial Cancer Video TC, GNYC Treatment and Clinical Trials, GYNC Newly Diagnosed, GYNC Video ND, GYNC Video TC, Gynecological Cancers /by Kara Rayburn

What Treatment Options and Factors Should Be Considered for Endometrial Cancer? from Patient Empowerment Network on Vimeo.

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Endometrial cancer treatment options take different factors into account, but what are they? Expert Dr. Ebony Hoskins explains key factors that play into treatment decisions and shares advice to be proactive in your care.

Dr. Ebony Hoskins is a board-certified gynecologic oncologist at MedStar Washington Hospital Center and assistant professor of Clinical Obstetrics and Gynecology at Georgetown University Medical Center.

[ACT]IVATION TIP

“…asking your doctor based off the stage and grade, ‘What is the standard of care?’”

Are Endometrial Cancer Outcomes Worse for Underrepresented Patients?

Related Resources:

How Can Endometrial Cancer Patients Advocate for Better Care?

What Treatment Options Are Available for Advanced Endometrial Cancer?

Transcript:

Mikki:

Dr. Hoskins, please walk us through a treatment option for endometrial cancer by stage, and what other factors should be considered when making treatment, the decisions?

Dr. Ebony Hoskins:

So this question used to be so easy where I would say, okay, if you had stage I, if someone is diagnosed with stage I, they don’t need any further treatment. If they have stage two, they may need radiation. Stage III and IV, typically chemotherapy and radiation. And I think what makes the difference in this question now is that it all depends not just in stage, but the type of cancer or the grade. So it’s one is the extent of disease. And the second question is the type of cancer. So some there could be a higher risk endometrial cancer, that’s early stage where we may need to give chemotherapy.

So I think my activation tip for this question would be asking your doctor based off the stage and grade, “What is the standard of care?” We always want standard of care, because that’s a golden standard in terms of treatment. And looking at all the options are into that care. Usually standard of care is either usually one, maybe two options. And I think looking at the whole scenario in terms of the patient, any other side effects that they may have, medications or diagnosis.

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