This month the focus is on cancer screening and education, both equally important in improving patient outcomes. A new metabolite has been found in urine of patients with a form of liver cancer, allowing for a new urine screening tool to detect the cancer. Pancreatic cancer is one of the deadliest cancers; education about symptom recognition could help save lives with earlier detection. Scientists are studying how cells move through the body with the hope of preventing metastasis of cancer cells in the future.
Urine Test Hope for Early Liver Cancer Diagnosis
Staff at the Cancer Research UK Beatson Institute in Glasgow have identified a metabolite never found before in mammals which could indicate the presence of the disease reports BBC News. Currently, there is no urine test available for any kind of cancer. Liver cancer is usually diagnosed through blood tests, ultrasound scans, and surgery. Scientists discovered a new metabolite while studying glutamine synthetase, which is a protein present in normal liver tissue of mice. This new metabolite is called N5-methylglutamine and is present in the urine of patients with a specific type of liver cancer. This specific liver cancer has a gene mutation of beta-catenin. This urine test will indicate if the patient has this form of liver cancer and may also be used to monitor growth of tumors. Diagnosis of liver cancer is often in the late stages, making the patient’s outcome less favorable. This test could allow for earlier diagnosis and treatment, leading to better patient outcomes. Click to read the full story.
14 Signs of Deadliest Cancer You’re Most Likely to Ignore
Pancreatic cancer, one of the deadliest forms of the disease, is particularly hard to spot as it does not cause and signs of symptoms in the early stages reports The US Sun. This cancer typically has a lower survivability rate of death in less than 3 months of diagnosis. The pancreas is located behind the stomach and under the liver, this location makes it difficult to treat. The purpose of the pancreas is to put digestive enzymes in the stomach to break down food. It is also responsible for releasing hormones that regulate blood sugar. Understanding some common symptoms associated with pancreatic cancer could help with earlier cancer detection. Due to the pancreas’ functions, common symptoms are indigestion, abdominal or back pain, nausea, and loss of appetite. More symptoms can include weight loss, fatigue, changes in bowel habits, and difficulty swallowing food. Patients can experience jaundice, itchiness, and depression or anxiety. Pancreatic cancer diagnosis can sometimes be detected with a recent diabetes diagnosis since the pancreas regulates blood sugar. Finally, blood clots can occasionally be a sign of cancer. Click to read the full story.
A Look at How Cancer Cells Move and Metastasize Could Help Doctors Stop Them From Spreading
Instead of focusing on just the effect of the “solid” environment of cells, researchers are turning toward their “fluid” environment reports Popular Science. Scientists are studying how fluids affect cell migration. In cancer cells, the fluid between the cells is thicker than healthy cells. This thicker fluid causes cancer cells to move and spread quicker. The cancer cells maintain a memory after being in the thicker fluid and continue to move faster and leak out into surrounding tissue causing metastasis. Metastasis is usually what kills cancer patients. This new knowledge that fluid viscosity affects cell migration can be used to create potential drug targets to reduce the spread of cancer. Click to read the full story.
Dana Kaiser is a professional writer and a strong patient advocate, learning from experience during her 22-year career as a nurse.